Haha Tony's message is awesome. Never thought of it.
Personally (for nervous girls only, if she's a natural chatter box then this won't work at all) I always try to ease her tension a little bit and build comfort (since she already feels sky-high tension). You can do this by calling it out:
It seems like you're kinda nervous and excited, which is awesome! But you don't have to be so nervous, I already think you're kinda rad because you talked about how you like animals and you're a Harry Potter nerd (or whatever she talked about, as long as it's something that you connect on).
And afterwards just moving on without giving her time to respond so she can process it without feeling like she's being put in the spotlight. "But anyways, what do you think of that blank over there?" or even "But anyways, I remember you saying something about race cars but you didn't really finish your thought."
For the natural chatter boxes (who aren't nervous, but just talkative in general) the only thing that I've found to work at all for me is to project a calmer energy and take control over the conversation. But to be honest, the natural chatty Kathy's I don't really connect to all that well and usually end up avoiding. Though I'll keep Tony's response in my back pocket, think it could work.